BDBM50347830 CHEMBL1802425

SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O

InChI Key InChIKey=PQRQSEBAGUHPRH-XDIGFQIYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50347830   

TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Institute For Research And Innovation In Biomedicine (Irib)

Curated by ChEMBL
LigandPNGBDBM50347830(CHEMBL1802425)
Affinity DataIC50:  8.73E+3nMAssay Description:Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Institute For Research And Innovation In Biomedicine (Irib)

Curated by ChEMBL
LigandPNGBDBM50347830(CHEMBL1802425)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as increase Ca2+ mobilization after 3 mins by Fluo-4 AM-based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Institute For Research And Innovation In Biomedicine (Irib)

Curated by ChEMBL
LigandPNGBDBM50347830(CHEMBL1802425)
Affinity DataEC50:  739nMAssay Description:Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Institute For Research And Innovation In Biomedicine (Irib)

Curated by ChEMBL
LigandPNGBDBM50347830(CHEMBL1802425)
Affinity DataEC50:  739nMAssay Description:Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed