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BDBM50354502 CHEMBL1836788

SMILES: O=C1Nc2ccccc2C1CCCCN1CCN(CC1)c1ccccn1

InChI Key: InChIKey=AHJOSYULWRUECL-UHFFFAOYNA-N

Data: 2 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354502   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50354502
PNG
(CHEMBL1836788)
Show SMILES O=C1Nc2ccccc2C1CCCCN1CCN(CC1)c1ccccn1
Show InChI InChI=1/C21H26N4O/c26-21-18(17-7-1-2-9-19(17)23-21)8-4-6-12-24-13-15-25(16-14-24)20-10-3-5-11-22-20/h1-3,5,7,9-11,18H,4,6,8,12-16H2,(H,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometry


J Med Chem 54: 6657-69 (2011)


Article DOI: 10.1021/jm200547z
BindingDB Entry DOI: 10.7270/Q25Q4WGZ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50354502
PNG
(CHEMBL1836788)
Show SMILES O=C1Nc2ccccc2C1CCCCN1CCN(CC1)c1ccccn1
Show InChI InChI=1/C21H26N4O/c26-21-18(17-7-1-2-9-19(17)23-21)8-4-6-12-24-13-15-25(16-14-24)20-10-3-5-11-22-20/h1-3,5,7,9-11,18H,4,6,8,12-16H2,(H,23,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
56n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat frontal cortex membrane after 45 mins by scintillation counting


J Med Chem 54: 6657-69 (2011)


Article DOI: 10.1021/jm200547z
BindingDB Entry DOI: 10.7270/Q25Q4WGZ
More data for this
Ligand-Target Pair