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BDBM50362357 CHEMBL1939764

SMILES: COc1ccc2CCCC(NC(=O)C[C@H]3N(C=CNC3=O)S(=O)(=O)c3ccc(C)cc3)c2c1

InChI Key: InChIKey=CLGAUZZJHBJRJP-ZREVVVSZNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50362357
PNG
(CHEMBL1939764)
Show SMILES COc1ccc2CCCC(NC(=O)C[C@H]3N(C=CNC3=O)S(=O)(=O)c3ccc(C)cc3)c2c1
Show InChI InChI=1/C24H27N3O5S/c1-16-6-10-19(11-7-16)33(30,31)27-13-12-25-24(29)22(27)15-23(28)26-21-5-3-4-17-8-9-18(32-2)14-20(17)21/h6-14,21-22H,3-5,15H2,1-2H3,(H,25,29)(H,26,28)/t21?,22-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 178n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...


Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair