BDBM26645 (5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidine-2,4-dione::CHEMBL1946643::thiazolidine-2,4-dione, 23a

SMILES OC1=NC(=O)C(S1)=Cc1ccc(Br)cc1

InChI Key InChIKey=WOJYBXTWFNRUTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26645   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26645((5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  2.80E+4nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM26645((5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  4.35E+4nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM26645((5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  228nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26645((5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  90nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed