BDBM50365209 CHEMBL1950388

SMILES: COc1ccc(\C=C\C(=O)c2cccc(Br)c2)cc1OC

InChI Key: InChIKey=CIADKJFJYZARIL-SOFGYWHQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM50365209 (CHEMBL1950388) Show SMILES COc1ccc(\C=C\C(=O)c2cccc(Br)c2)cc1OC Show InChI InChI=1S/C17H15BrO3/c1-20-16-9-7-12(10-17(16)21-2)6-8-15(19)13-4-3-5-14(18)11-13/h3-11H,1-2H3/b8-6+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of TNF-alpha-induced NF-kappaB p65 nuclear translocation in human A549 cells after 2 hrs by fluorescence assay				Eur J Med Chem 50: 393-404 (2012) Article DOI: 10.1016/j.ejmech.2012.02.023 BindingDB Entry DOI: 10.7270/Q2XW4K83
					More data for this Ligand-Target Pair