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BDBM50365209 CHEMBL1950388

SMILES: COc1ccc(\C=C\C(=O)c2cccc(Br)c2)cc1OC

InChI Key: InChIKey=CIADKJFJYZARIL-SOFGYWHQSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365209   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM50365209
PNG
(CHEMBL1950388)
Show SMILES COc1ccc(\C=C\C(=O)c2cccc(Br)c2)cc1OC
Show InChI InChI=1S/C17H15BrO3/c1-20-16-9-7-12(10-17(16)21-2)6-8-15(19)13-4-3-5-14(18)11-13/h3-11H,1-2H3/b8-6+
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of TNF-alpha-induced NF-kappaB p65 nuclear translocation in human A549 cells after 2 hrs by fluorescence assay


Eur J Med Chem 50: 393-404 (2012)


Article DOI: 10.1016/j.ejmech.2012.02.023
BindingDB Entry DOI: 10.7270/Q2XW4K83
More data for this
Ligand-Target Pair