BDBM50375126 CHEMBL255583
SMILES CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)Cc1ccccc1
InChI Key InChIKey=VDCBVWYXKRWDEB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50375126
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by ChEMBL
Abbott Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by ChEMBL
Abbott Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I]-CXCL10 from mouse CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair