BDBM50377370 CHEMBL260846

SMILES: Nc1nc(cs1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=KGPBNLSPHADRDS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50377370 (CHEMBL260846) Show SMILES Nc1nc(cs1)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C10H6F4N2S/c11-7-2-1-5(3-6(7)10(12,13)14)8-4-17-9(15)16-8/h1-4H,(H2,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Agonist activity at TPO receptor				Bioorg Med Chem Lett 18: 3000-6 (2008) Article DOI: 10.1016/j.bmcl.2008.03.052 BindingDB Entry DOI: 10.7270/Q2474BRS
					More data for this Ligand-Target Pair