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BDBM50377370 CHEMBL260846

SMILES: Nc1nc(cs1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=KGPBNLSPHADRDS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377370   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombopoietin receptor


(Homo sapiens (Human))
BDBM50377370
PNG
(CHEMBL260846)
Show SMILES Nc1nc(cs1)-c1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H6F4N2S/c11-7-2-1-5(3-6(7)10(12,13)14)8-4-17-9(15)16-8/h1-4H,(H2,15,16)
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Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at TPO receptor


Bioorg Med Chem Lett 18: 3000-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.052
BindingDB Entry DOI: 10.7270/Q2474BRS
More data for this
Ligand-Target Pair