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BDBM50379322 CHEMBL2011832

SMILES: CC(C)[C@@H](N1CC(=O)Nc2ccc(Oc3ccccc3)cc2C1=O)C(=O)N1CCC(CC1)N[C@H](C)c1ccccc1

InChI Key: InChIKey=ARZUYFDFMKIKHV-PFFIRVMKNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379322   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM50379322
PNG
(CHEMBL2011832)
Show SMILES CC(C)[C@@H](N1CC(=O)Nc2ccc(Oc3ccccc3)cc2C1=O)C(=O)N1CCC(CC1)N[C@H](C)c1ccccc1
Show InChI InChI=1/C33H38N4O4/c1-22(2)31(33(40)36-18-16-25(17-19-36)34-23(3)24-10-6-4-7-11-24)37-21-30(38)35-29-15-14-27(20-28(29)32(37)39)41-26-12-8-5-9-13-26/h4-15,20,22-23,25,31,34H,16-19,21H2,1-3H3,(H,35,38)/t23-,31-/s2
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PC sid
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Similars

Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human GHSR1a receptor assessed as intracellular Ca2+ concentration by aequorin luminescent assay


Bioorg Med Chem Lett 22: 2046-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.014
BindingDB Entry DOI: 10.7270/Q21J9BRV
More data for this
Ligand-Target Pair