BDBM50381178 CHEMBL2018387
SMILES CCC[C@H](O)[C@H](CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)NC(C)C)C(F)(F)F
InChI Key InChIKey=ACFBGSHYQKWEDV-DQEYMECFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50381178
Affinity DataIC50: 4.70nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125-I]MCP1 from CCR2 on human PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair