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BDBM50384640 CHEMBL2036954

SMILES: O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1

InChI Key: InChIKey=JDQWWGPAMKFJTN-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384640   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50384640
PNG
(CHEMBL2036954)
Show SMILES O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1
Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(5-4-7-2-1-3-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)
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UniProtKB/SwissProt

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GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation


ACS Med Chem Lett 3: 63-68 (2012)


Article DOI: 10.1021/ml200243g
BindingDB Entry DOI: 10.7270/Q29K4C8X
More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Mus musculus)
BDBM50384640
PNG
(CHEMBL2036954)
Show SMILES O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1
Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(5-4-7-2-1-3-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR109a


ACS Med Chem Lett 3: 63-68 (2012)


Article DOI: 10.1021/ml200243g
BindingDB Entry DOI: 10.7270/Q29K4C8X
More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Rattus norvegicus)
BDBM50384640
PNG
(CHEMBL2036954)
Show SMILES O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1
Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(5-4-7-2-1-3-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at rat GPR109a


ACS Med Chem Lett 3: 63-68 (2012)


Article DOI: 10.1021/ml200243g
BindingDB Entry DOI: 10.7270/Q29K4C8X
More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50384640
PNG
(CHEMBL2036954)
Show SMILES O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1
Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(5-4-7-2-1-3-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 67n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human GPR109b


ACS Med Chem Lett 3: 63-68 (2012)


Article DOI: 10.1021/ml200243g
BindingDB Entry DOI: 10.7270/Q29K4C8X
More data for this
Ligand-Target Pair