BDBM50386859 CHEMBL2048293

SMILES: OC(=O)CC1CCn2c1cc1cc(ccc21)-c1noc(n1)-c1cc(OC(F)(F)F)cc(c1)C#N

InChI Key: InChIKey=HHVPFOZVFPAJBT-UHFFFAOYSA-N

Data: 7 IC50  17 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50386859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 2 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 5 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 5 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 4 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 3 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 3 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 2 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Mouse)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Mouse)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Rat)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Rat)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.760	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM50386859 (CHEMBL2048293) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair