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BDBM50390609 CHEMBL2069589

SMILES: O=C(Nc1cc(c[nH]c1=O)-c1cc[nH]n1)[C@H](Cc1ccccc1)NCc1cscn1

InChI Key: InChIKey=UFIHOFMGHSWUFF-LGWFVXIRNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM50390609
PNG
(CHEMBL2069589)
Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1cc[nH]n1)[C@H](Cc1ccccc1)NCc1cscn1
Show InChI InChI=1/C21H20N6O2S/c28-20-19(9-15(10-23-20)17-6-7-25-27-17)26-21(29)18(8-14-4-2-1-3-5-14)22-11-16-12-30-13-24-16/h1-7,9-10,12-13,18,22H,8,11H2,(H,23,28)(H,25,27)(H,26,29)/t18-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 200n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...


Bioorg Med Chem Lett 22: 5942-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.063
BindingDB Entry DOI: 10.7270/Q2VH5PXT
More data for this
Ligand-Target Pair