BDBM50398744 CHEMBL2179629

SMILES OC(=O)c1cc(ccc1Cl)-c1cccc(COc2ccc3c(c2)sn(C2CC2)c3=O)c1

InChI Key InChIKey=RBQZSTHTHNKFHW-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50398744   

TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu8R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu7R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu6R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu4R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu3R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu1R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398744(CHEMBL2179629)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu5R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed