BDBM50399947 CHEMBL2181236

SMILES CCCN1CCN(C(=O)c2cnccc2Oc2cc(Cl)ccc2Cl)c2ccccc12

InChI Key InChIKey=KPYYZMLWXHSKDH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399947   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399947(CHEMBL2181236)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399947(CHEMBL2181236)
Affinity DataEC50:  76nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed