BDBM50026917 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione::8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione(BMY-7378)::BMY 7378::BMY-7378::CHEMBL1256934::CHEMBL13647::CHEMBL543741

SMILES: COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key: InChIKey=AYYCFGDXLUPJAQ-UHFFFAOYSA-N

Data: 89 KI  3 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 93 hits for monomerid = 50026917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.02	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.778	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.959	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		42.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Guinea pig)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026917 (CHEMBL13647 | BMY 7378 | 8-{2-[4-(2-Methoxy-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair