BDBM50161093 (R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile::2-Chloro-6-[((2R)-3-([1,1-dimethyl-2-(2-naphthalenyl)ethyl]-amino)-2-hydroxypropyl)oxy]benzonitrile hydrochloride::2-Chloro-6-[(R)-3-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-2-hydroxy-propoxy]-benzonitrile::CHEMBL180672::CHEMBL2112075

SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@H](COc3cccc(c3C#N)Cl)O

InChI Key: InChIKey=PZUJQWHTIRWCID-UHFFFAOYSA-N

Data: 24 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50161093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Bovine)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0580	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rat)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rat)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Human)	BDBM50161093 (CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair