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BDBM50414491 CHEMBL559204

SMILES: OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1cccs1

InChI Key: InChIKey=AHGROBOIZXOOSW-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414491   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50414491
PNG
(CHEMBL559204)
Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1cccs1
Show InChI InChI=1S/C14H13N3O2S2/c18-14(19)12-6-13(16-15-12)17(7-10-3-5-20-9-10)8-11-2-1-4-21-11/h1-6,9H,7-8H2,(H,15,16)(H,18,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a<1.00E+4n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at GPR109a receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay


Bioorg Med Chem Lett 19: 4207-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.108
BindingDB Entry DOI: 10.7270/Q2GF0TJJ
More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50414491
PNG
(CHEMBL559204)
Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1cccs1
Show InChI InChI=1S/C14H13N3O2S2/c18-14(19)12-6-13(16-15-12)17(7-10-3-5-20-9-10)8-11-2-1-4-21-11/h1-6,9H,7-8H2,(H,15,16)(H,18,19)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 141n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay


Bioorg Med Chem Lett 19: 4207-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.108
BindingDB Entry DOI: 10.7270/Q2GF0TJJ
More data for this
Ligand-Target Pair