BDBM50417916 CHEMBL1668564::US8618114, 1.2.5(1)

SMILES CNc1nn2c(C)cc(COC)nc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=AKYBXIOZAWNEGP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417916   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50417916(CHEMBL1668564 | US8618114, 1.2.5(1))
Affinity DataKi:  0.269nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50417916(CHEMBL1668564 | US8618114, 1.2.5(1))
Affinity DataIC50:  4nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
In DepthDetails US Patent