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BDBM50419387 CHEMBL1916255

SMILES: CCCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1

InChI Key: InChIKey=CSXJDDPSJQGTQW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419387   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM50419387
PNG
(CHEMBL1916255)
Show SMILES CCCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1
Show InChI InChI=1S/C23H28N4O3S/c1-4-9-18(5-2)25-23(28)21-16-24-27(19-10-7-6-8-11-19)22(21)26-31(29,30)20-14-12-17(3)13-15-20/h6-8,10-16,18,26H,4-5,9H2,1-3H3,(H,25,28)
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UniProtKB/SwissProt

DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 316n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 21: 6456-60 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.085
BindingDB Entry DOI: 10.7270/Q2WD41VZ
More data for this
Ligand-Target Pair