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BDBM52328 3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-1H-pyrrol-1-yl)benzoic acid::3-[2-[(E)-[3-(2-cyanobenzyl)-2,4-diketo-thiazolidin-5-ylidene]methyl]pyrrol-1-yl]benzoic acid::3-[2-[(E)-[3-[(2-cyanophenyl)methyl]-2,4-bis(oxidanylidene)-1,3-thiazolidin-5-ylidene]methyl]pyrrol-1-yl]benzoic acid::3-[2-[(E)-[3-[(2-cyanophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]pyrrol-1-yl]benzoic acid::3-[2-[(E)-[3-[(2-cyanophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]-1-pyrrolyl]benzoic acid::MLS000539676::SMR000162049::cid_1729040

SMILES: OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O

InChI Key: InChIKey=MULYWAQNBZWZHL-UDWIEESQSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 52328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
POsterior Segregation family member (pos-1)


(Caenorhabditis elegans)
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
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UniProtKB/TrEMBL

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n/an/an/an/a 3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q28G8J4C
More data for this
Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5


(Caenorhabditis elegans)
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
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n/an/an/an/a 3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2D798VP
More data for this
Ligand-Target Pair
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1


(Homo sapiens (Human))
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
PDB
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Article
PCBioAssay
n/an/a 5.19E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


Article DOI: 10.1016/j.bioorg.2015.08.001
BindingDB Entry DOI: 10.7270/Q2V986KM
More data for this
Ligand-Target Pair
probable DNA dC->dU-editing enzyme APOBEC-3A


(Homo sapiens (Human))
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
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n/an/a 1.49E+4n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q24F1P6P
More data for this
Ligand-Target Pair
DNA dC->dU-editing enzyme APOBEC-3G


(Homo sapiens (Human))
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
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n/an/a 3.70E+4n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2862DX0
More data for this
Ligand-Target Pair
large T antigen


(Simian virus 40)
BDBM52328
PNG
(3-(2-{[3-(2-cyanobenzyl)-2,4-dioxo-1,3-thiazolidin...)
Show SMILES OC(=O)c1cccc(c1)-n1cccc1\C=C1\SC(=O)N(Cc2ccccc2C#N)C1=O
Show InChI InChI=1S/C23H15N3O4S/c24-13-16-5-1-2-6-17(16)14-26-21(27)20(31-23(26)30)12-19-9-4-10-25(19)18-8-3-7-15(11-18)22(28)29/h1-12H,14H2,(H,28,29)/b20-12+
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n/an/an/an/a 1.69E+4n/an/an/an/a



Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay


Assay Description
Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2ZK5F47
More data for this
Ligand-Target Pair