BDBM53933 (5Z)-5-(3-chloro-4-hydroxy-5-methoxy-benzylidene)-2-phenyl-2-thiazolin-4-one::(5Z)-5-[(3-chloranyl-5-methoxy-4-oxidanyl-phenyl)methylidene]-2-phenyl-1,3-thiazol-4-one::(5Z)-5-[(3-chloro-4-hydroxy-5-methoxyphenyl)methylidene]-2-phenyl-1,3-thiazol-4-one::(5Z)-5-[(3-chloro-4-hydroxy-5-methoxyphenyl)methylidene]-2-phenyl-4-thiazolone::5-(3-chloro-4-hydroxy-5-methoxybenzylidene)-2-phenyl-1,3-thiazol-4(5H)-one::5-(3-chloro-4-hydroxy-5-methoxybenzylidene)-2-phenylthiazol-4(5H)-one::CHEMBL1339294::MLS000676732::SMR000298378::cid_717270
SMILES COc1cc(\C=C2/SC(=NC2=O)c2ccccc2)cc(Cl)c1O
InChI Key InChIKey=BTIAAMWQYVYEFI-ZROIWOOFSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 53933
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc
Curated by PubChem BioAssay
Srmlsc
Curated by PubChem BioAssay
Affinity DataIC50: 2.00E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production preincubated for 15 mins measured after ...Checked by AuthorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in S100 supernatant assessed as inhibition of (5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid production pre...Checked by AuthorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in S100 supernatant assessed as inhibition of LTB4 production preincubated for 15 mins measured after 10 mins by HPLC me...Checked by AuthorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as inhibition of (5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic a...Checked by AuthorMore data for this Ligand-Target Pair