BDBM54429 4-hydroxy-6-phenyl-2-{[3-(trifluoromethyl)benzyl]sulfanyl}-5-pyrimidinecarbonitrile::4-keto-6-phenyl-2-[[3-(trifluoromethyl)benzyl]thio]-1H-pyrimidine-5-carbonitrile::4-oxidanylidene-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methylsulfanyl]-1H-pyrimidine-5-carbonitrile::4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methylsulfanyl]-1H-pyrimidine-5-carbonitrile::4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methylthio]-1H-pyrimidine-5-carbonitrile::MLS001165305::SMR000549815::cid_1471857

SMILES: FC(F)(F)c1cccc(CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c1

InChI Key: InChIKey=VLQLCRVTTSCBBQ-UHFFFAOYSA-N

Data: 5 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 54429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.34E+3	n/a	n/a	n/a	n/a
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Nucleotide-binding oligomerization domain-containing protein 1 (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tumor necrosis factor (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM54429 (4-oxo-6-phenyl-2-[[3-(trifluoromethyl)phenyl]methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair