BDBM64569 US9428505, Comparative: Example 1

SMILES Cc1cc(ccc1CCS(=O)(=O)N1CCC2(CC1)N=C(NC2=O)c1cccc(OC(F)(F)F)c1)N1C(=O)CNC1=O

InChI Key InChIKey=REOKUYXIRRUCMN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 64569   

TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rattus norvegicus (Rat))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM64569(US9428505, Comparative: Example 1)
Affinity DataEC50:  2.30E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetParathyroid hormone [32-65](Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM64569(US9428505, Comparative: Example 1)
Affinity DataEC50:  4.80E+3nMpH: 7.4Assay Description:HKRK-B7 or LLC-PK1 cells were seeded into a 96-well plate at 1×105 cells/well and incubated overnight. On the following day, 50 μl of cAMP assay...More data for this Ligand-Target Pair
In DepthDetails US Patent