BDBM84286 US9694016, 574

SMILES: CCOc1nnc(cc1N1CCOCC1)-c1cc(NC(=O)c2ccc(CNC)c(c2)C(F)(F)F)ccc1C

InChI Key: InChIKey=ZAOMDELYPOSTSG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 84286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM84286 (US9694016, 574) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E] (Human)	BDBM84286 (US9694016, 574) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair