BDBM85098 N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide::RS-102221

SMILES: COc1cc(OC)c(cc1NS(=O)(=O)c1ccc(cc1)C(F)(F)F)C(=O)CCCCN1CCC2(CC1)NC(=O)NC2=O

InChI Key: InChIKey=HZZZZODVDSHQRG-UHFFFAOYSA-N

Data: 36 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 85098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		3.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		7.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Rabbit)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Mouse)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1A (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Mouse)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Rabbit)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Guinea pig)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Substance-P receptor (Human)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor 3 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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