BDBM8964 CHEMBL75274::Homodimeric Tacrine Analog 3c::N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Dimer 3c::Tacrine-Based Inhibitor 2g

SMILES: C(CCCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12

InChI Key: InChIKey=ZIDVXYDWJIVBSC-UHFFFAOYSA-N

Data: 2 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 8964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	-11.9	n/a	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM8964 (CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair