BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM8994 6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Analogue 11

SMILES: COc1cc2nc3CCCCc3c(N)c2cc1OC

InChI Key: InChIKey=KZBQUUNPSWNEND-UHFFFAOYSA-N

Data: 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8994
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Human)	BDBM8994 (6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8994 (6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8994 (6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair