BDBM9014 7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-5-metoxy-3-yl)-ethyl]-amide::N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptanamide::Tacrine-Melatonin Hybrid 7b

SMILES: COc1ccc2[nH]cc(CCNC(=O)CCCCCCNc3c4CCCCc4nc4ccccc34)c2c1

InChI Key: InChIKey=NNXPYYPDXHQYMI-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 9014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Bovine)	BDBM9014 (N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	8.0	30
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Carboxylic ester hydrolase (Horse)	BDBM9014 (N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM9014 (N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM9014 (N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM9014 (N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair