BDBM9047 Bis-THA inhibitor 5::CHEMBL73800::Hexylene-Linked Bis-tacrine::Homodimeric Tacrine Analog 3a::N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]-1,2,3,4-tetrahydroacridin-9-amine

SMILES: C(CCCNc1c2CCCCc2nc2ccccc12)CCNc1c2CCCCc2nc2ccccc12

InChI Key: InChIKey=IYNUCVAQGDCTFO-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 9047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
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Cholinesterase (Human)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	119	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM9047 (CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair