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Found 29 with Last Name = 'snyder' and Initial = 'js'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140012(US8901310, Comparator B)
Affinity DataIC50:  0.350nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  0.526nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140013(US8901310, Comparator C)
Affinity DataIC50:  1.10nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140015(US8901310, Comparator E)
Affinity DataIC50:  1.10nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140015(US8901310, Comparator E)
Affinity DataIC50:  1.18nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140013(US8901310, Comparator C)
Affinity DataIC50:  1.22nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140014(US8901310, Comparator D)
Affinity DataIC50:  1.30nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140009(US8901310, Example 1 )
Affinity DataIC50:  1.31nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140016(US8901310, Comparator F)
Affinity DataIC50:  1.90nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140014(US8901310, Comparator D)
Affinity DataIC50:  2.06nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140017(US8901310, Comparator G)
Affinity DataIC50:  2.10nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140017(US8901310, Comparator G)
Affinity DataIC50:  2.13nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140019(US8901310, Comparator I)
Affinity DataIC50:  2.80nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140012(US8901310, Comparator B)
Affinity DataIC50:  4nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  4.20nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140018(US8901310, Comparator H)
Affinity DataIC50:  4.30nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140020(US8901310, Comparator J)
Affinity DataIC50:  4.58nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140016(US8901310, Comparator F)
Affinity DataIC50:  7nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140011(US8901310, Comparator A)
Affinity DataIC50:  7.10nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140018(US8901310, Comparator H)
Affinity DataIC50:  8.03nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140019(US8901310, Comparator I)
Affinity DataIC50:  9.12nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  14.9nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140011(US8901310, Comparator A)
Affinity DataIC50: >36.4nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  42nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  60nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  79nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140020(US8901310, Comparator J)
Affinity DataIC50:  291nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140021(US8901310, Comparator K)
Affinity DataIC50:  895nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140011(US8901310, Comparator A)
Affinity DataIC50: >1.00E+3nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent