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Found 22 Enz. Inhib. hit(s) with all data for entry = 10268
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524064(US11136336, Example 15)
Affinity DataIC50:  9nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524060(US11136336, Example 11)
Affinity DataIC50:  10nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524041(3-({3-[(2S)-2-(4-chlorophenyl)-2-hydroxyethyl]-1,2...)
Affinity DataIC50:  13nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524067(7-Bromo-3-((3-(2-(4-chlorophenyl)-2-hydroxyethyl)-...)
Affinity DataIC50:  14nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524061(US11136336, Example 12)
Affinity DataIC50:  15nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524065(US11136336, Example 16)
Affinity DataIC50:  16nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524052(US11136336, Example 3)
Affinity DataIC50:  19nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524051(US11136336, Example 2)
Affinity DataIC50:  20nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524053(US11136336, Example 4)
Affinity DataIC50:  33nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524063(US11136336, Example 14)
Affinity DataIC50:  33nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524056(US11136336, Example 7)
Affinity DataIC50:  34nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524068(3-((3-(2-(4-Chlorophenyl)-2-hydroxyethyl)-1,2,4-ox...)
Affinity DataIC50:  35nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524066(1-({3-[2-(4-Chlorophenyl)-2-hydroxyethyl]-1,2,4-ox...)
Affinity DataIC50:  36nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524062(US11136336, Example 13)
Affinity DataIC50:  37nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524070(5-((3-(2-(4-Chlorophenyl)-2-hydroxyethyl)-1,2,4-ox...)
Affinity DataIC50:  41nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524055(US11136336, Example 6)
Affinity DataIC50:  48nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524054(US11136336, Example 5)
Affinity DataIC50:  48nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50157702(CHEMBL3786639 | JMC 2016, 59, 2794-2809, Example 3...)
Affinity DataIC50:  52nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524059(US11136336, Example 10)
Affinity DataIC50:  52nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524057(US11136336, Example 8)
Affinity DataIC50:  56nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524069(1-((3-(2-(4-Chlorophenyl)-2-hydroxyethyl)-1,2,4-ox...)
Affinity DataIC50:  67nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524058(US11136336, Example 9)
Affinity DataIC50:  78nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent