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Found 39 with Last Name = 'bono' and Initial = 'cp'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385150(CHEMBL2035650)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of HPGDSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385142(CHEMBL2035651)
Affinity DataIC50:  2.34nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385144(CHEMBL2035653)
Affinity DataIC50:  8.26nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287637((S)-3-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-naphthale...)
Affinity DataIC50:  31nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366440(CHEMBL1790415 | SC-67655)
Affinity DataIC50:  50nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287642((S)-3-({1-[(S)-6-Amino-2-(3-bicyclo[2.2.1]hept-2-y...)
Affinity DataIC50:  76nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTumor necrosis factor receptor superfamily member 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287632(CHEMBL1253325 | PKYVKQNTLKLAT (HA306-318 peptide))
Affinity DataIC50:  80nMAssay Description:Compound was tested for its ability to compete for binding to DR4 using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366444(CHEMBL1790402)
Affinity DataIC50:  100nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287650((S)-3-({1-[2-Cyclohexyl-2-((R)-3-cyclohexyl-butyry...)
Affinity DataIC50:  130nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287636((S)-3-({1-[(S)-6-Amino-2-((S)-3-cyclohexyl-butyryl...)
Affinity DataIC50:  162nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287628((S)-3-({1-[(S)-2-(3-Cyclohexyl-propionylamino)-3-m...)
Affinity DataIC50:  170nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366439(CHEMBL1793835)
Affinity DataIC50:  178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366439(CHEMBL1793835)
Affinity DataIC50:  178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287630((S)-3-({1-[(S)-6-Amino-2-(3-cycloheptyl-propionyla...)
Affinity DataIC50:  178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287626((S)-2-((2S,3R)-2-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-...)
Affinity DataIC50:  180nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385143(CHEMBL2035652)
Affinity DataIC50:  274nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385149(CHEMBL2035649)
Affinity DataIC50:  280nMAssay Description:Inhibition of HPGDSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287640(1-[(S)-2-((R)-3-Cyclohexyl-butyrylamino)-3-methyl-...)
Affinity DataIC50:  293nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287649((S)-3-({1-[2-((R)-3-Cyclohexyl-butyrylamino)-2-phe...)
Affinity DataIC50:  424nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385145(CHEMBL2035654)
Affinity DataIC50:  662nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287645(1-[(S)-2-(3-Cyclohexyl-propionylamino)-3-methyl-bu...)
Affinity DataIC50:  755nMAssay Description:Compound was tested for its ability to compete for binding to DR4 using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385147(CHEMBL2035656)
Affinity DataIC50:  845nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287646((S)-3-({1-[(2S,3R)-2-((R)-3-Cyclohexyl-butyrylamin...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385146(CHEMBL2035655)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366443(CHEMBL1790407)
Affinity DataIC50:  1.80E+3nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366441(CHEMBL1790416)
Affinity DataIC50:  2.50E+3nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287643((S)-3-({1-[(S)-2-(3-Cyclohexyl-propionylamino)-3-(...)
Affinity DataIC50:  3.15E+3nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTumor necrosis factor receptor superfamily member 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287634((S)-4-[(S)-2-((1S,2R)-1-Carbamoyl-2-hydroxy-propyl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Compound was tested for its ability to compete for binding to DR4 using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50385148(CHEMBL2035648)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of HPGDSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287652(3-({(S)-1-[2-(3-Cyclohexyl-butyrylamino)-3-methyl-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287633(3-({(S)-(S)-1-[2-((S)-3-Cyclohexyl-butyrylamino)-6...)
Affinity DataIC50:  1.00E+4nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366442(CHEMBL1790414)
Affinity DataIC50:  1.60E+4nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287654((S)-4-((S)-2-Carbamoyl-pyrrolidin-1-yl)-3-({1-[(S)...)
Affinity DataIC50:  2.33E+4nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287653(1-[(S)-2-((R)-3-Cyclohexyl-butyrylamino)-3-methyl-...)
Affinity DataIC50:  4.37E+4nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287629((S)-4-[(S)-2-((S)-2-Amino-1-propylcarbamoyl-ethylc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287631(3-({1-[(S)-2-((R)-3-Cyclohexyl-butyrylamino)-3-met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287635(1-[(S)-2-(3-Cyclohexyl-propionylamino)-3-(3H-imida...)
Affinity DataIC50: >1.00E+5nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287644(1-[(S)-2-(2-Cyclohexylamino-acetylamino)-3-methyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287639((S)-3-({1-[(S)-6-Amino-2-(4-cyclohexyl-heptanoylam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article