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Found 90 with Last Name = 'gardner' and Initial = 'tl'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284844(2-Biphenyl-4-yl-3-methyl-quinoline-4-carboxylic ac...)
Affinity DataKi:  1.70nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284826(CHEMBL288708 | Sodium; 2-biphenyl-4-yl-6-fluoro-3-...)
Affinity DataKi:  8nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069968(CHEMBL104209 | Sodium; 9-fluoro-3-phenyl-5,6-dihyd...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284843(2-Biphenyl-4-yl-3-methyl-6-trifluoromethyl-quinoli...)
Affinity DataKi:  8.40nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284861(2-Biphenyl-4-yl-6-fluoro-quinoline-4-carboxylic ac...)
Affinity DataKi:  10nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069950(CHEMBL321060 | Sodium; 9-fluoro-3-o-tolyl-5,6-dihy...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284834(2-Biphenyl-4-yl-3,6-dimethyl-quinoline-4-carboxyli...)
Affinity DataKi:  10nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284867(CHEMBL43639 | Sodium; 6-fluoro-2-(2'-fluoro-4'-hyd...)
Affinity DataKi:  11nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataKi:  12nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069959(Brequinar sodium | CHEMBL300058 | Sodium; 6-fluoro...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284853(2-Biphenyl-4-yl-6-fluoro-3-methoxy-quinoline-4-car...)
Affinity DataKi:  13nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069939(CHEMBL106467 | Sodium; 9-fluoro-3-p-tolyl-6H-thioc...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284858(2-Biphenyl-4-yl-6-fluoro-3-methylsulfanyl-quinolin...)
Affinity DataKi:  13nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069951(CHEMBL104302 | Sodium; 9-fluoro-3-phenyl-6H-thioch...)
Affinity DataKi:  17nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284838(9-Fluoro-3-phenyl-5,6-dihydro-benzo[c]acridine-7-c...)
Affinity DataKi:  17nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069943(CHEMBL106515 | Sodium; 9-fluoro-3-(2-methoxy-pheny...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284862(2-Biphenyl-4-yl-6-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  20nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284830(CHEMBL38421 | Sodium; 6-fluoro-3-methyl-2-(4'-meth...)
Affinity DataKi:  24nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069958(CHEMBL104146 | Sodium; 9-fluoro-3-o-tolyl-5H-6-thi...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069948(CHEMBL107209 | Sodium; 9-fluoro-3-(3-methoxy-pheny...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284846(2-Biphenyl-4-yl-5-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  25nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069941(CHEMBL321163 | Sodium; 9-fluoro-3-o-tolyl-6H-thioc...)
Affinity DataKi:  27nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284864(2-(4-Cyclohexyl-phenyl)-6-fluoro-3-methyl-quinolin...)
Affinity DataKi:  28nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284860(6-Fluoro-3-methyl-2-(4-phenoxy-phenyl)-quinoline-4...)
Affinity DataKi:  29nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284842(2-Biphenyl-4-yl-3-ethyl-6-fluoro-quinoline-4-carbo...)
Affinity DataKi:  30nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069971(CHEMBL105175 | Sodium; 3-phenyl-9-trifluoromethyl-...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069940(CHEMBL320204 | Sodium; 9-fluoro-3-(2-fluoro-phenyl...)
Affinity DataKi:  34nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069960(CHEMBL104136 | Sodium; 9-fluoro-3-m-tolyl-6H-thioc...)
Affinity DataKi:  37nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284855(CHEMBL38242 | Sodium; 2-(4'-bromo-biphenyl-4-yl)-6...)
Affinity DataKi:  38nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069949(CHEMBL322274 | Sodium; 9-fluoro-3-(2-trifluorometh...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201921(2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-car...)
Affinity DataKi:  40nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284837(2-(4-tert-Butyl-phenyl)-6-fluoro-3-methyl-quinolin...)
Affinity DataKi:  40nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069944(CHEMBL106865 | Sodium; 9-fluoro-3-p-tolyl-5,6-dihy...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069966(CHEMBL104824 | Sodium; 9-fluoro-3-(3-trifluorometh...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069957(CHEMBL107642 | Sodium; 9-fluoro-3-phenyl-6H-chrome...)
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284852(2-(2'-Fluoro-biphenyl-4-yl)-3-methyl-[1,7]naphthyr...)
Affinity DataKi:  48nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284820(CHEMBL38978 | Sodium; 6-fluoro-2-(3'-fluoro-biphen...)
Affinity DataKi:  50nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069970(CHEMBL107224 | Sodium; 9-fluoro-3-thiophen-3-yl-5,...)
Affinity DataKi:  52nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069947(CHEMBL441276 | Sodium; 9-fluoro-3-(4-methoxy-pheny...)
Affinity DataKi:  55nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284859(CHEMBL41799 | Sodium; 6-fluoro-3-methyl-2-(4-thiop...)
Affinity DataKi:  56nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069961(CHEMBL104766 | Sodium; 9-fluoro-3-m-tolyl-5,6-dihy...)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284854(6-Fluoro-2-(4-hexyl-phenyl)-3-methyl-quinoline-4-c...)
Affinity DataKi:  60nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284851(6-Fluoro-3-methyl-2-(3-phenoxy-phenyl)-quinoline-4...)
Affinity DataKi:  63nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069973(CHEMBL104167 | Sodium; 9-fluoro-3-m-tolyl-5,6-dihy...)
Affinity DataKi:  81nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069946(CHEMBL108213 | Sodium; 9-fluoro-3-m-tolyl-5H-6-thi...)
Affinity DataKi:  135nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069952(CHEMBL108327 | Sodium; 9-fluoro-5,5-dioxo-3-phenyl...)
Affinity DataKi:  139nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284869(CHEMBL38639 | Sodium; 2-(4'-chloro-biphenyl-4-yl)-...)
Affinity DataKi:  140nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284841(2-Biphenyl-4-yl-8-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  150nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069945(CHEMBL106529 | Sodium; 9-fluoro-3-(3-methoxy-pheny...)
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069972(CHEMBL320245 | Sodium; 9-fluoro-3-phenyl-5H-6-thia...)
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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