Compile Data Set for Download or QSAR
maximum 50k data
Found 606 with Last Name = 'marshall' and Initial = 'l'
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204580(CHEMBL247667 | N-phenethyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591075(CHEMBL5200118)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591046(CHEMBL5202342)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591054(CHEMBL5179922)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591066(CHEMBL5190023)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204580(CHEMBL247667 | N-phenethyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591045(CHEMBL5209076)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545768(CHEMBL4641127)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204590((S)-6-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-5...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204590((S)-6-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-5...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591070(CHEMBL5208600)
Affinity DataIC50:  8nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591079(CHEMBL5196751)
Affinity DataIC50:  8nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204586(6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545779(CHEMBL4642563)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591075(CHEMBL5200118)
Affinity DataIC50:  9nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545782(CHEMBL4637695)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591081(CHEMBL5193210)
Affinity DataIC50:  10nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591044(CHEMBL5202445)
Affinity DataIC50:  11nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204585((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204583((S)-(4-ethylpiperazin-1-yl)(4-(5-phenyl-4-((tetrah...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204576(6-(4-morpholinophenyl)-5-phenyl-N-(2-(piperazin-1-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069616((2R,3S)-N*1*-Hydroxy-2-{2-[(E)-hydroxyimino]-2-phe...)
Affinity DataIC50:  12nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204583((S)-(4-ethylpiperazin-1-yl)(4-(5-phenyl-4-((tetrah...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069604(CHEMBL118054 | [(2S,3R)-3-((S)-1-Carbamoyl-2-pheny...)
Affinity DataIC50:  13nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204588(6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-(...)
Affinity DataIC50:  14nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204591(5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  14nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591077(CHEMBL5201930)
Affinity DataIC50:  15nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591065(CHEMBL5170361)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591072(CHEMBL5172690)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204585((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591066(CHEMBL5190023)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069601((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591065(CHEMBL5170361)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204576(6-(4-morpholinophenyl)-5-phenyl-N-(2-(piperazin-1-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591064(CHEMBL5199369)
Affinity DataIC50:  17nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545769(CHEMBL4645325)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591054(CHEMBL5179922)
Affinity DataIC50:  20nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase(Rattus norvegicus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 12aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069583((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-2-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082226((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069620((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50:  20nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 606 total ) | Next | Last >>
Jump to: