BDBM50068270 (E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one::(E)-3-[5-(1,1-Dimethyl-allyl)-4-hydroxy-2-methoxy-phenyl]-1-(4-hydroxy-phenyl)-propenone::3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one::3-[5-((E)-1,1-Dimethyl-allyl)-4-hydroxy-2-methoxy-phenyl]-1-(4-hydroxy-phenyl)-propenone::CHEMBL139702::Licochalcone A

SMILES: COc1cc(O)c(cc1\C=C\C(=O)c1ccc(O)cc1)C(C)(C)C=C

InChI Key: InChIKey=KAZSKMJFUPEHHW-UHFFFAOYSA-N

Data: 46 IC50  3 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 54 hits for monomerid = 50068270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	442	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	367	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sialidase (Clostridium perfringens)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50068270 (3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair