BDBM50241426 3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one::CHEMBL258405::Icilin::Icillin

SMILES: c1ccc(c(c1)N2CC=C(NC2=O)c3cccc(c3)[N+](=O)[O-])O

InChI Key: InChIKey=RCEFMOGVOYEGJN-UHFFFAOYSA-N

Data: 1 IC50  6 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50241426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Human)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rat)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Human)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Human)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rat)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rat)	BDBM50241426 (3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair