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Found 6 of ec50 for monomerid = 50241426
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  60nMAssay Description:Activation of TRPM8 channelMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
National Research Council

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as induction of intracellular Ca2+ level by Fluo-4-AM dye based spectrofluorimetryMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
National Research Council

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as increase in intracellular calcium concentration by fluorimet...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  300nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  300nMAssay Description:Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed