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BDBM4920 3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic acid::3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propionic Acid::Indolin-2-one deriv. 9g
SMILES: COc1cccc(c1)-c1ccc2\C(=C\c3[nH]c4CCCCc4c3CCC(O)=O)C(=O)Nc2c1
InChI Key: InChIKey=FUXHNAHZJZOIIP-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM4920![]() (3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3...) | GoogleScholar | UniChem | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4920![]() (3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3...) | GoogleScholar | UniChem | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Human) | BDBM4920![]() (3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3...) | GoogleScholar | UniChem | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM4920![]() (3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3...) | GoogleScholar | UniChem | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM4920![]() (3-{2-[6-(3-Methoxyphenyl)-2-oxo-1,2-dihydroindol-3...) | GoogleScholar | UniChem | n/a | n/a | 8.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||