BDBM50143314 (+)-Epibatidine::(-)-epibatidine::(1R,2R,4S)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane (epibatidine)::CHEMBL298826::EPIBATIDINE

SMILES: Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2

InChI Key:

Data: 18 KI  1 IC50  4 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50143314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28	n/a	n/a	7.4	20
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Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
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Nicotinic acetylcholine receptor alpha 5 subunit (House fly)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholine-binding protein (Great pond snail)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.67	n/a	n/a	n/a	7.4	25
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					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Great pond snail)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0835	n/a	n/a	n/a	7.4	25
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Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Great pond snail)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Soluble acetylcholine receptor (California sea hare)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		7.40	-10.9	n/a	n/a	n/a	n/a	n/a	7.4	20
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143314 (CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair