BindingDB PrimarySearch

BDBM50005711 CHEBI:46024::GNF-Pf-1011::TRICHOSTATIN::Trichostatin A::Trichostatin A (TSA)::US10011611, Trichostatin A::US10722597, Compound Trichostatin::US11535598, Compound Trichostatin A::US20230322747, Compound trichostatin A::US9265734, TSA

SMILES: C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C

InChI Key: InChIKey=RTKIYFITIVXBLE-UHFFFAOYSA-N

Data: 30 KI 322 IC50 8 Kd 1 EC50 1 ITC

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 395 hits for monomerid = 50005711
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	20.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 [395-489] (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	29.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 4 [627-1085] (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 5 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.05	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 7 [518-592] (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	472	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 9 [604-1066] (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 11 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	23.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 3 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 4 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	34.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 5 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 7 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 9 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	70.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	22.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.90	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 3 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.41	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	213	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 4 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 5 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	871	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 7 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	663	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 9 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.721	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	11.6	n/a	n/a	n/a	n/a	7.5	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	12.1	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	15.3	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
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Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.22	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
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Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	11.5	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 3 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.58	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	70.1	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 4 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 5 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 7 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 9 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.22	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 11 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	18.3	n/a	n/a	n/a	n/a	8.0	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.83	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 3 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.33	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Human)	BDBM50005711 (GNF-Pf-1011 \| CHEBI:46024 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	39.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair

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