BDBM10309 5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2,3-dione::5-[1-(Pyrrolidinyl)sulfonyl]isatin::Isatin Sulfonamide 20

SMILES: O=C1Nc2ccc(cc2C1=O)S(=O)(=O)N1CCCC1

InChI Key: InChIKey=QKCWUYHXHMXOLG-UHFFFAOYSA-N

Data: 8 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 10309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-3 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-3 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+3	-8.11	2.80E+3	n/a	n/a	n/a	n/a	7.5	30
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Caspase-7 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-1 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-9 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-2 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-4 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-6 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10309 (5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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