BDBM10331 (S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione::1-[(4-fluorophenyl)methyl]-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione::CHEMBL372607::Pyrrolidine Isatin Analogue 11c

SMILES: Fc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2ccccc2)cc1

InChI Key: InChIKey=BLQICVVKCWCIMT-UHFFFAOYSA-N

Data: 6 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 10331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-3 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.1	n/a	n/a	n/a	n/a	7.4	37
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Caspase-7 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-1 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-6 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-7 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19.8	n/a	n/a	n/a	n/a
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Caspase-1 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
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Caspase-6 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
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Caspase-3 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	78.6	n/a	n/a	n/a	n/a
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Caspase-3 (Human)	BDBM10331 ((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.0	n/a	n/a	n/a	n/a	n/a	n/a
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