BDBM11834 3-{2-[(dimethylamino)methyl]-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::BIM-11

SMILES: CN(C)CC1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1c[nH]c3ccccc13)c1ccccc21

InChI Key: InChIKey=KAUXQCPPAWLYAB-UHFFFAOYSA-N

Data: 1 Kd  1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Human)	BDBM11834 (3-{2-[(dimethylamino)methyl]-1H,2H,3H,4H-pyrido[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 11834

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM11834 (3-{2-[(dimethylamino)methyl]-1H,2H,3H,4H-pyrido[1,...)	Serine/threonine-protein kinase PIM (Human)		GoogleScholar		-8.49	-5.28	-3.29	6.60	7.5	10
	TBA				Details of this binding reaction