BDBM18807 2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL400364::Pyrrolo[2,3-d]pyrimidine analogue, 2

SMILES: Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=IXCJWBJTGZAHRW-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 18807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	30
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Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	30
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Thymidylate synthase (Escherichia coli (strain K12))	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	7.4	30
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Dihydrofolate reductase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Rat)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.47E+6	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Thymidylate synthase (Escherichia coli)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thymidylate synthase (Human)	BDBM18807 (2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair