BDBM19590 (2S)-N-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-4-methyl-2-[(3-methylphenyl)formamido]pentanamide::arylaminoethyl amide, 3f

SMILES CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCN1CCc2ccccc12

InChI Key InChIKey=IYQYYEJBWONMDP-NRFANRHFSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19590   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19590((2S)-N-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-4-meth...)
Affinity DataKi:  88nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19590((2S)-N-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-4-meth...)
Affinity DataKi:  230nM ΔG°:  -9.41kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19590((2S)-N-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-4-meth...)
Affinity DataKi:  310nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed