BDBM22396 (1R,2S,3S,5S)-3-(4-chlorophenyl)-2-[5-(4-fluorophenyl)-1,3-thiazol-2-yl]-8-methyl-8-azabicyclo[3.2.1]octane::WIN 35,065-2::WIN35,065-2::Win 35,065::methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate::troparil, 1R-(exo,exo)-isomer

SMILES: COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccccc1)N2C

InChI Key: InChIKey=OMBOXYLBBHNWHL-UHFFFAOYSA-N

Data: 9 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 22396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	7.4	4
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Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Norepinephrine transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	-7.80	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22396 (methyl (1R,2S,3S,5S)-8-methyl-3-phenyl-8-azabicycl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair