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BDBM23413 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one::Apigenin-7,4'-dimethylether::Genkwanin::apigenin dimethylether

SMILES: COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)cc2o1

InChI Key: InChIKey=LZERJKGWTQYMBB-UHFFFAOYSA-N

Data: 1 IC50  1 Other

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23413   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM23413
PNG
(5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen...)
Show SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)cc2o1
Show InChI InChI=1S/C17H14O5/c1-20-11-5-3-10(4-6-11)15-9-14(19)17-13(18)7-12(21-2)8-16(17)22-15/h3-9,18H,1-2H3
PDB
MMDB

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KEGG
PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 2.78E+4n/an/an/an/an/a37



Eberhard Karls University of Tuebingen



Assay Description
The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...


Chembiochem 11: 2579-88 (2010)


Article DOI: 10.1002/cbic.201000487
BindingDB Entry DOI: 10.7270/Q21C1VDT
More data for this
Ligand-Target Pair
alpha-Amylase


(Homo sapiens (human))
BDBM23413
PNG
(5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen...)
Show SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)cc2o1
Show InChI InChI=1S/C17H14O5/c1-20-11-5-3-10(4-6-11)15-9-14(19)17-13(18)7-12(21-2)8-16(17)22-15/h3-9,18H,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
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KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/a6.022



Nestle Research Center



Assay Description
The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...


J Med Chem 51: 3555-61 (2008)


Article DOI: 10.1021/jm800115x
BindingDB Entry DOI: 10.7270/Q237771Z
More data for this
Ligand-Target Pair