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BDBM243677 US9428456, 1.298

SMILES: COc1ccc(NC(=O)c2ccc(F)cc2)cc1CN1CCC(CC1)C(=O)NC(C)(C)C

InChI Key: InChIKey=CTWDLNAUIDFXSL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243677   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 7 (CXCR7)


(Homo sapiens (Human))
BDBM243677
PNG
(US9428456, 1.298)
Show SMILES COc1ccc(NC(=O)c2ccc(F)cc2)cc1CN1CCC(CC1)C(=O)NC(C)(C)C
Show InChI InChI=1S/C25H32FN3O3/c1-25(2,3)28-24(31)18-11-13-29(14-12-18)16-19-15-21(9-10-22(19)32-4)27-23(30)17-5-7-20(26)8-6-17/h5-10,15,18H,11-14,16H2,1-4H3,(H,27,30)(H,28,31)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 19n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...


US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair