BDBM32319 (5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylene]-2-thiazolin-4-one::(5Z)-5-[[5-(4-methylphenyl)-2-furanyl]methylidene]-2-(4-morpholinyl)-4-thiazolone::(5Z)-5-[[5-(4-methylphenyl)furan-2-yl]methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one::2-Morpholin-4-yl-5-(5-p-tolyl-furan-2-ylmethylene)-thiazol-4-one::MLS000723666::SMR000305261::cid_1115796

SMILES Cc1ccc(cc1)-c1ccc(\C=C2/SC(=NC2=O)N2CCOCC2)o1

InChI Key InChIKey=FMPMZUAARSQGKI-ATVHPVEESA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32319   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataEC50:  7.86E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataEC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataIC50:  9.69E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataEC50:  4.46E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProthrombin(Bos taurus (Bovine))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataIC50:  7.72E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32319((5Z)-2-morpholino-5-[[5-(p-tolyl)-2-furyl]methylen...)
Affinity DataEC50:  8.90E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay