BDBM34849 6-fluoranyl-2-(2-methylphenyl)-1,2-benzothiazol-3-one::6-fluoro-2-(2-methylphenyl)-1,2-benzisothiazol-3(2H)-one::6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one::6-fluoro-2-(o-tolyl)-1,2-benzothiazol-3-one::MLS000729299::SMR000307577::cid_1510379

SMILES: Cc1ccccc1-n1sc2cc(F)ccc2c1=O

InChI Key: InChIKey=BUIZTXXZBDUOCR-UHFFFAOYSA-N

Data: 17 IC50  7 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 34849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large T antigen (SV40)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a
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Phosphomannomutase 2 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitochondrial peptide methionine sulfoxide reductase (Bovine)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.04E+5	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate 1-dehydrogenase (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA dC->dU-editing enzyme APOBEC-3A (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
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DNA dC->dU-editing enzyme APOBEC-3G (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.02E+3	n/a	n/a	n/a	n/a	n/a	25
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Glucose-6-phosphate 1-dehydrogenase (Leuconostoc mesenteroides)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphotransferase (Trypanosoma brucei brucei (strain 927/4 GUTat10.1))	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.95E+3	n/a	n/a	n/a	n/a	7.4	23
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Neutrophil cytosol factor 1 [S99G] (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
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M18 aspartyl aminopeptidase (Plasmodium falciparum (isolate 3D7))	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	648	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 4 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4 gamma 1 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 16 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 19 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 7 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 8 (Human)	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a
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Phosphotransferase (Trypanosoma brucei brucei (strain 927/4 GUTat10.1))	BDBM34849 (MLS000729299 | 6-fluoranyl-2-(2-methylphenyl)-1,2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
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